57 SEPARATE INDEPENDANT REPORTS SHOWING THAT ASPARTAMEIS UNSAFE
A list of independent studies showing aspartame to be unsafe:This is in spite of industry claims that all the studies show it to besafe. Don’t think these are the only such reports in existence that showsthe “official” version of the facts to be a lot of lies, either! All ofthe testimony of aspartame victims, of which we know of there being atleast 30,000 individual such cases on record (a drop in the bucket whencompared to the cases NOT on record), just between what has been reportedto the FDA, to Mission Possible, and what has been posted in the Guestbooksat www.dorway.com and www.aspartame.com
Here are some of the references and citations from an articleabout independent testing on aspartame by Barbara Mullarkey, the journalistwho has been writing about aspartame since its approve. The articlewas titled NEUROTOXIC POTENTIAL OF ASPARTAME. At a later date wewill probably scan it in.
1. Stegink, L.: Filer, L.J. Jr. Aspartame Physiology and Biochemistry.University of Iowa College of Medicine. Iowa City, IA Marcel Dekker,Inc. 1984.
2. Camfield, P.R.: Camfield, J.M.: Dooley, J.M.: et al with generalizedabsence epilepsy: A double-blind controlled study. Neurology (42) 1000-1003(May 1992)
3. Boehm, M.: Bada, J. Racemization of aspartic acid and phenylalaninein the sweetener aspartame at 100 degrees C. Proc. Natl. Acad. Sci. USA(81) August 1984.
4. Walton, R. G. “Seizure and mania after high intake of aspartame.”Psychopathology 17:98-106 (1984)
5. Drake, M.E. “Panic Attacks and Excessive Aspartame Ingestion.”The Lancet (Sept 13, l986) p. 631
6. Walton, R. G. “The Possible Role of Aspartame in Seizure Induction”Proceedings of the First International Meeting on Dietary Phenylalanineand Brain Function. (May 8-10 1987) pp.495-499
7. Epstein, C. M.: Trotter, J.F.: et al “EEG Mean Frequenciesare Sensitive indices of Phenylalanine Effects on Normal Brain.” Electroencephalographyand Clinical Neurophysiology 72:133-139 (1989)
8. Pinto, J.M.B.” Maher, T. J. “Administration of Aspartame PotentiatesPentlyeneterazole and Fluorothyl-Induced Seizure in Mice.” Neuropharmacology27 (1):51-55 (l988)
9. Olney, John “Excitatory Neurotoxins as Food Additives: An Evaluation of Risk.” Neurotoxicology 2:163-192 (1980)
10. Koehler S.M.: Glaros, A. “The effect of aspartame on migraineheadache.” Headache 28:000-000 (l988)
11. Edmeada, J. Editorial: “Aspartame and Headache.” Headache,pp.64-65 (February, 1988)
12. Lipton, R. B.; Newman, L. C.: Solomon, S. “Aspartame andheadache, (re:Schiffman et al study),” New England Journal of Medicine318 (18): 1200-1201 (May 5, 1988)
13. Steinmetzer, R.V.: Kunkel, R.S. “Aspartame and Headache”New England Journal of Medicine 318 (18): 1201 (May 5, 1988)
14. Koehler, Shirley; and Glaros, Alan. “The Effect of Aspartameon Migraine Headache.” Headache 28 (1):10-14 (l988)
15. Olney, J. W.; and Ho, Ol. “Brain damage in Infant Mice FollowingOral Intake of Glutamate, Aspartate or Cysteine.” Nature 227:609-611 (August8, 1970)
16. Olney, J. W. “Excitotoxic Food Additives – Relevance of AnimalStudies to Human Safety.” Neurological Behavioral Toxicology andTeratology 6:455-462 (l984).
17. Olney, J. W.; Labruyere, J: DeGubaret, T. “Brain Damage inMice from Voluntary Ingestion of Glutamate and Aspartame.” NeurobehavioralToxicology 2:125-129 (l980)
18. Roberts, H. J. “Does Aspartame Cause Human Brain cancer?” Journalof Advances in Medicine 4 (4): 231-241 (Winter, 1991).
19. Potenza, D.” El-Mailakh, Rif S. “Aspartame: Clinical Update.”Connecticut Medical Journal 53 (7): 395-400 (l989)
20. Sardesai, V.M.: Holliday, J.F.; et al. “Effect of Aspartame inNormal and Diabetic Rats.” Biochemical Archives 2:237-243 (l986)
21. Federal Register 48:54993-54995 (Dec 8, l983)
22. Yokigoshi, H.: Roberts, C. F>: Caballero, B.: Wurtman, R.J. “Effects of Aspartame and Glucose Administration on Brain and PlasmaLevels of Large Neutral Amino Acids and Brain 5-Hydroxyindoles.” AmericanJournal of Clinical Nutrition. 40:1-7 (July 1, 1984)
23. Krause, W.:Halminksi, M.” et al. “Biochemical and NeuropsychologicalEffects of Elevated Plasma Phenylalanine in Patients with Treated Phenylketonuria.” Journal of Clinical Investigation 75: 40-48 (January, 1985).
24. Pardridge, W.M. “Potential Effects of the Dipeptide Sweetener Aspartameon the Brain. Nutrition and the Brain 7:199-241 (l986)
25. Gaines, S. M.: Bada, J.I. “Reversed Phase, High-Performance LiquidChromatographic Separation of Aspartame Diastereomeric Decomposition Products.”Journal of Chromatography. 389-:219-225 (l987)
26. Filer, L. J.; Stegnink. L.D. “Effect of Aspartame on Plasma PhenylalanineConcentration in Humans.” Proceedings of the First International Meetingon Dietary Phenylalanine and the Brain Function (May 8-10, l987) pp 25-26
27. Matalon, R.: Michals, K.:et al. “Aspartame Consumption in NormalIndividuals and Carriers for Phenylketonuria (PKU).” Proceedings of theFirst International Meeting on Dietary Phenylalanine and Brain Function(May 8-10, l987) pp. 81-93
28. Matalon, R. Michals, K.” Sullivan, D.; et al. “Aspartame Consumptionin Normal Individuals and Carriers for Phenylketonuria (PKU).” Universityof Illinois at Chicago, Department of Pediatrics, Nutrition and MedicalDietetics and Epidemiology and Biometry, Chicago, Illinois (l986).
29. Tocci, P.M.: Beber, B. “Anomalous Phenylalanine Loading Responsesin Relation to Cleft Lip and Cleft Palate.” Pediatrics 52: 109-113 (Julyl973)
30. Steilman, S.D.:Garfinkel, L. “Artificial Sweetener and OneYear Weight Change Among Women.” Preventative Medicine 15:195-202 (l986)
31. Blundell, J.E.: Hill, A.H. “Paradoxical Effects of an IntenseSweetener (Aspartame) on Appetite.” The Lancet (May 10, l986) pp.l092-1093.
32. Garriga, M., MD; and Metcalf, D.,MD. “Aspartame intolerance”Annals of Allergy 61:63-66 (December 1988)
33. United States General Accounting Office/HRD-87-86, Food andDrug Administration’s Approval of Aspartame. (June l987)
34. Council Report: Aspartame review of safety issues.Journal of the American Medical Association l985:254 (3):400
35. Johns,D.R., MD, Letter to the Editor. The New England Journalof Medicine (August 14, 1986)
36. Novick, N.J. “Aspartame-induced granulomatous panniculitis.”Annals of Internal Medicine 102:206-207 (l985)
37. McCauliffe, D.: and Poitras, K. “Aspartame-induced lobularpanniculitis.” J of the American Academy of Dermatology 24 (2):298-299(February 1991)
38. Kulezycki,A.Jr. “Aspartame induced urticaria. Annals of InternalMedicine 104:207-208 (l986)
39. Wurtman, R.J. “Aspartame: possible effect on seizure susceptibility.”Lancet 2:1060. (l985)
40. Schainker, N. and Olney, J.W. “Glutamate Type Hypothalamic PituitarySyndrome in Mice Treated with Aspartame or Cysteate in Infancy.” Journal of Neutral Trans. 35: 207-215 (l974)
41. Reynolds, W. A.: Butler, V.” Lemley-Johnson, N. “HypothalamicMorphology Following ingestion of Aspartame of MSG in the Neonatal Rodentand Primate: A Preliminary Report” Journal of Toxicology andEnvironmental Health 2:471-480 (l976)
42. Pizzi, W.J.:Tabor, J.M.:Barnhart,J. “Somatic, Behavioraland Reproductive Disturbances in Mice Following Neonatal Administrationof Sodium L-Aspartate.” Pharmacological Biochemical Behavior 9::481-485(l976)
43. Stegnik, L.D.: Brummel, M.C.; et al, “Blood Methanol Concentrationsin Normal Adult Subjects Administered Abuse dose of Aspartame.” J of ToxicologicalEnvironmental Health 7:281-290 (l981)
44. Monte, Woodrow, “Aspartame: Methanol and the Public Health,”Journal of Applied Nutrition 36(1):42-54 (l984).
45. Bergeron, R.:Cardinal, J.” et al. “Prevention of MethanolToxicity by Ethanol Therapy.” New England Journal of Medicine (December9, 1982) pp. 1528
46. Tsang, W.S.;Clarke, M.A.; Parrish, F.W. “Determination ofAspartame and Its Breakdown Products in Soft Drinks by Reverse-Phase Chromatographywith UV Detection.” Journal of Agricultural Fd. Chemicals 33:734-738(l985)
47. Davoli, E.; Cappeilini, L.’ et al. “Serum Methanol Concentrationsin Rats and in Men after a Single Dose of Aspartame.” Fed. Chemical Toxicology24 (3):187-189 (l986).
48. Uribe, M. “Potential Toxicity of a New Sugar Substitute inPatients with Liver Disease.” New England Journal of Medicine. 306(3):173-174 (Jan 21, 1981).
49. Wurtman, R.J. “Neurochemical Changes Following High DoseAspartame with Dietary Carbohydrates.” New England Journal of Medicine309:7 (August 18, 1982).
50. Sharma, R.P.; Coulombe, R.A., Jr. “Effects of Repeated Dosesof Aspartame on Serotonin and its Metabolite in Various Regions of theMouse Brain.” Toxicology Program, Department of Animal, Dairy andVeterinary Sciences. Utah State University. (l986).
51. Young, S.N.: Smith, S.E.; et al. “Tryptophan Depletion Causesa Rapid Lowering of Mood in Normal Males.” Psychopharmocology. 87: 173-177(l985).
52. Padridge, W.M. “The Safety of Aspartame.” J of the AmericanMedical Association 256 (19):2678. (November 21, l986).
53. Roberts, H.J. “New Perspectives Concerning Alzheimer’s Disease.”On Call (August 1989) pp. 14-16
54. Walton, R.G.: Hudak, R.: and Green-Waite, R.J. “Adverse REactionsto Aspartame: Double-blind Challenge in Patients from a VulnerablePopulation.” Biological Psychiatary pp. 13-17 (l993).
55. Lipton, S.A.: Rosenberg, P.A. “Excitatory Amino Acids asa Final common Pathway for Neurologic Disorders.” New England Journalof Medicine 330 (9):613-622 (l994).
56. Dow-Edwards, D.” Scribani, L.: and Riley, E.P. “ImpairedPerformance on Odor-Aversion Testing Follow Prenatal Aspartame Exposurein the Guinea Pig.” Neurotoxicology and Teratoiogy 11:413-416 (l989).
57. Millstone, E. “Sweet and Sour: The Unanswered Questionsabout Aspartame.” The Scoiogist Volume 24, Number 2 (March/April1994).
Here are some comments from Betty Martini, Mission Possible International,9270 State Bridge Road Suite 215, Duluth, Georgia 30097, E-mail: [email protected]who compiled this list:
It should be noted that the study by Dr. Diana Dow-Edwards was originallyfunded by the NutraSweet Company. When she got disastrous resultsthey withdrew their funding and Dr. Dow-Edwards had to pay for the studyherself. Then the NutraSweet Company refused to accept it. Remember thatindictment was sought for fraud on ones funded by Searle. U.S. AttorneySam Skinner went to work for Searle’s law firm defending the caserather than indicting them. Had he done what was asked NutraSweetwould probably not be in the market today.
Cynthia Crossen in her book THE TAINTED TRUTH; THE MANIPULATION OFFACT IN AMERICA, says “The read to hell was paved with the flood of corporateresearch dollars which in 1991 had burgeoned to over $2.1 billion. Researchersare working for people who don’t like negative findings and who aren’tlikely to fund further research by those who produce them. ..” “In today’scorporate-dominated information market truth has become to belong to thosewho commission it.”
For those who want more information on the politics and “flawed tests”funded by Searle check Mark Gold’s web page: http://www.holisticmed.com/aspartame/